KIT 抗体 (FITC)
(8 references)Our Local Distributor
北京 101111
Quick Overview for KIT 抗体 (FITC) (ABIN638436)
抗原
See all KIT 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Anti-Hu CD117 FITC
-
特异性
- The mouse monoclonal antibody 104D2 detects extracellular part of CD117 / c-Kit protooncogen.
-
交叉反应 （详细）
- Human, Non-Human Primates, Bovine
-
纯化方法
- Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
-
免疫原
- MOLM-1 megakaryocytic cells
-
亚型
- IgG1 kappa
-
-
anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 350-440) antibody
KIT 适用: 人, 小鼠, 大鼠 FACS, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 321-520) antibodyKIT 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 343-527) antibodyKIT 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mast/stem Cell Growth Factor Receptor (KIT) (Internal Region) antibodyVerified KIT 适用: 人 WB, FACS, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Mast/stem Cell Growth Factor Receptor (KIT) (pTyr703) antibodyKIT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mast/stem Cell Growth Factor Receptor (KIT) (pTyr721) antibodyKIT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 546-976) antibodyKIT 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2E3 unconjugated
anti-Mast/stem Cell Growth Factor Receptor (KIT) antibodyKIT 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1C5 unconjugated
anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 26-285) antibodyKIT 适用: 人 WB, FACS, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 106-135) antibodyKIT 适用: 人, 小鼠 WB, FACS, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
-
限制
- 仅限研究用
-
-
-
溶解方式
- No reconstitution is necessary.
-
缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
-
Do not freeze.
Avoid prolonged exposure to light. -
储存条件
- 4 °C
-
储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
-
-
-
: "Isolation, characterization, and differentiation of thy1.1-sorted pancreatic adult progenitor cell populations." in: Stem cells and development, Vol. 18, Issue 10, pp. 1389-98, (2009) (PubMed).
: "Identification of functional endothelial progenitor cells suitable for the treatment of ischemic tissue using human umbilical cord blood." in: Blood, Vol. 110, Issue 1, pp. 151-60, (2007) (PubMed).
: "Expression and functional significance of osteocalcin splicing in disease progression of hematological malignancies." in: Leukemia research, Vol. 30, Issue 10, pp. 1241-8, (2006) (PubMed).
: "Primitive acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo lack surface expression of c-kit (CD117)." in: Experimental hematology, Vol. 28, Issue 6, pp. 660-71, (2000) (PubMed).
: "Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies." in: Experimental animals / Japanese Association for Laboratory Animal Science, Vol. 49, Issue 2, pp. 97-110, (2000) (PubMed).
: "Signaling via Src family kinases is required for normal internalization of the receptor c-Kit." in: Blood, Vol. 94, Issue 6, pp. 1979-86, (1999) (PubMed).
: "Analysis of c-kit receptor dimerization by fluorescence resonance energy transfer." in: Blood, Vol. 91, Issue 3, pp. 898-906, (1998) (PubMed).
: "Functional and phenotypic characterization of cord blood and bone marrow subsets expressing FLT3 (CD135) receptor tyrosine kinase." in: Blood, Vol. 90, Issue 1, pp. 111-25, (1997) (PubMed).
-
: "Isolation, characterization, and differentiation of thy1.1-sorted pancreatic adult progenitor cell populations." in: Stem cells and development, Vol. 18, Issue 10, pp. 1389-98, (2009) (PubMed).
-
- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
-
别名
- CD117
-
背景
- KIT proto-oncogene, receptor tyrosine kinase,CD117 / c-Kit (stem cell factor receptor) is a 145 kDa receptor tyrosine kinase that regulates cell proliferation, adhesion, chemotaxis, apoptosis and other cell processes. Mutations of CD117 / c-Kit can lead to growth and progression of tumours. After binding of its ligand, SCF (stem cell factor), CD117 / c-Kit is autophosphorylated on its intracellular domains and activated. CD117 is expressed on pluripotent hematopoietic progenitor cells, mast cells and various cancer cells, e.g. acute myeloid leukemia cells.,c-Kit, PBT, SCFR
-
基因ID
- 3815
-
UniProt
- P10721
-
途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
抗原
-
