ICAM1 抗体
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北京 101111
Quick Overview for ICAM1 抗体 (ABIN636693)
抗原
See all ICAM1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified
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免疫原
- ICAM1 antibody was raised in rabbit using highly pure recombinant human ICAM-1 as the immunogen.
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应用备注
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ELISA: 0.5-2 µg/mL, Inhibition: 8 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized from PBS, pH 7.2.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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别名
- ICAM1
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背景
- ICAMs are members of the Ig superfamily of calcium-independent transmembrane glycoproteins. ICAM-1 is a ligand for lymphocyte function-associated (LFA) and Mac-1 integrins and the major human rhinovirus receptor. The primary function of ICAM-1 is to provide adhesion between endothelial cells and leukocytes after stress or injury. The human ICAM-1 gene codes for a 505 amino acid transmembrane glycoprotein containing a 29 amino acid cytoplasmic domain, a 23 amino acid transmembrane domain, and a 453 amino acid extracellular domain. Recombinant human ICAM-1 is a 49.5 kDa glycoprotein comprising the extracellular domain (453 amino acid residues) of ICAM-1.
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分子量
- 72-80 kDa (predicted detection band MW)
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
抗原
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