CCL3 抗体
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北京 101111
Quick Overview for CCL3 抗体 (ABIN636568)
抗原
See all CCL3 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified
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免疫原
- MIP1 alpha antibody was raised in rabbit using highly pure recombinant murine MIP-1 a as the immunogen.
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应用备注
- Optimal conditions should be determined byt he investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized from PBS, pH 7.2.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
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别名
- MIP1 alpha
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背景
- Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ, with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and Mouse MIP-1 alpha and MIP-1 beta are active on human and Mouse hematopoietic cells.
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分子量
- 7.8 kDa (predicted detection band MW)
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途径
- Cellular Response to Molecule of Bacterial Origin, Autophagy
抗原
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