PUMA 抗体
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北京 101111
Quick Overview for PUMA 抗体 (ABIN636281)
抗原
See all PUMA (BBC3) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity chromatography purified
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免疫原
- PUMA antibody was raised in rabbit using 17 residue sequence 29-55 [EQHLESPVPSAPGALAG] found in the exon-3-encoded region in the human PUMA-Alpha and PUMA-Beta forms of the protein as the immunogen.
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亚型
- IgG
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应用备注
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WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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浓度
- Lot specific
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缓冲液
- Affinity purified IgG supplied in PBS with 0.02 % NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
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别名
- PUMA
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背景
- PUMA (p53 upregulated modulator of apoptosis) is a target for activation by the p53 tumor-suppressor gene. Antisense inhibition of PUMA expression reduced the apoptotic response to p53, and PUMA is likely to play a role in mediating p53-induced cell death through the cytochrome c/Apaf-1-dependent pathway.
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途径
- p53 Pathway, Positive Regulation of Endopeptidase Activity
抗原
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