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PUMA 抗体

The 兔 多克隆 anti-PUMA antibody is suitable to detect PUMA in samples from 人. It has been validated for WB.
产品编号 ABIN636281
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PUMA 抗体 (ABIN636281)

抗原

See all PUMA (BBC3) 抗体
PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))

适用

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宿主

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克隆类型

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多克隆

标记

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This PUMA antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 纯化方法

    Affinity chromatography purified

    免疫原

    PUMA antibody was raised in rabbit using 17 residue sequence 29-55 [EQHLESPVPSAPGALAG] found in the exon-3-encoded region in the human PUMA-Alpha and PUMA-Beta forms of the protein as the immunogen.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:1,000
    Optimal conditions should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    Lot specific

    缓冲液

    Affinity purified IgG supplied in PBS with 0.02 % NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
  • 抗原

    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))

    别名

    PUMA

    背景

    PUMA (p53 upregulated modulator of apoptosis) is a target for activation by the p53 tumor-suppressor gene. Antisense inhibition of PUMA expression reduced the apoptotic response to p53, and PUMA is likely to play a role in mediating p53-induced cell death through the cytochrome c/Apaf-1-dependent pathway.

    途径

    p53 Pathway, Positive Regulation of Endopeptidase Activity
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