GNS 抗体 (C-Term)
Quick Overview for GNS 抗体 (C-Term) (ABIN635775)
抗原
See all GNS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- GNS antibody was raised against the C terminal of GNS
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纯化方法
- Affinity purified
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免疫原
- GNS antibody was raised using the C terminal of GNS corresponding to a region with amino acids PILRGASNLTWRSDVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDA
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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GNS Blocking Peptide, (ABIN5613817), is also available for use as a blocking control in assays to test for specificity of this GNS antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of GNS antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))
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别名
- GNS
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背景
- GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparin sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder ucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
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分子量
- 58 kDa (MW of target protein)
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途径
- Glycosaminoglycan Metabolic Process
抗原
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