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RNF139 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects RNF139 in WB. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN635236
发货至: 中国
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Quick Overview for RNF139 抗体 (N-Term) (ABIN635236)

抗原

See all RNF139 抗体
RNF139 (Ring Finger Protein 139 (RNF139))

适用

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  • 17
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  • 2
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  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 28
  • 4
  • 1

克隆类型

  • 30
  • 3
多克隆

标记

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  • 1
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  • 1
  • 1
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This RNF139 antibody is un-conjugated

应用范围

  • 24
  • 13
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  • 5
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  • 3
Western Blotting (WB)
  • 抗原表位

    • 15
    • 2
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    RNF139 antibody was raised against the N terminal of RNF139

    纯化方法

    Affinity purified

    免疫原

    RNF139 antibody was raised using the N terminal of RNF139 corresponding to a region with amino acids SQRSLFKFYTYSSAFLLAATSVLVNYYASLHIDFYGAYNTSAFGIELLPR
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    RNF139 Blocking Peptide, (ABIN5615888), is also available for use as a blocking control in assays to test for specificity of this RNF139 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of RNF139 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    RNF139 (Ring Finger Protein 139 (RNF139))

    别名

    RNF139

    背景

    RNF139 is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.

    分子量

    76 kDa (MW of target protein)
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