BACE2 抗体 (N-Term)
Quick Overview for BACE2 抗体 (N-Term) (ABIN635235)
抗原
See all BACE2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- BACE2 antibody was raised against the N terminal of BACE2
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纯化方法
- Affinity purified
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免疫原
- BACE2 antibody was raised using the N terminal of BACE2 corresponding to a region with amino acids PAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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BACE2 Blocking Peptide, (ABIN5612267), is also available for use as a blocking control in assays to test for specificity of this BACE2 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of BACE2 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
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别名
- BACE2
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背景
- Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene.
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分子量
- 37 kDa (MW of target protein)
抗原
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