SPPL2B 抗体 (N-Term)
Quick Overview for SPPL2B 抗体 (N-Term) (ABIN634985)
抗原
See all SPPL2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- SPPL2 B antibody was raised against the N terminal of SPPL2
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纯化方法
- Affinity purified
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免疫原
- SPPL2 B antibody was raised using the N terminal of SPPL2 corresponding to a region with amino acids VARGNCTFYEKVRLAQGSGARGLLIVSRERLVPPGGNKTQYDEIGIPVAL
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应用备注
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WB: 1 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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SPPL2B Blocking Peptide, (ABIN5616378), is also available for use as a blocking control in assays to test for specificity of this SPPL2B antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SPPL0 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))
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别名
- SPPL2B
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背景
- SPPL2B is a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways.
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分子量
- 56 kDa (MW of target protein)
抗原
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