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SPPL2B 抗体 (N-Term)

This anti-SPPL2B antibody is a 兔 多克隆 antibody detecting SPPL2B in WB 和 IHC. Suitable for 人.
产品编号 ABIN634985
发货至: 中国

Quick Overview for SPPL2B 抗体 (N-Term) (ABIN634985)

抗原

See all SPPL2B 抗体
SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))

适用

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宿主

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克隆类型

  • 11
多克隆

标记

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This SPPL2B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    特异性

    SPPL2 B antibody was raised against the N terminal of SPPL2

    纯化方法

    Affinity purified

    免疫原

    SPPL2 B antibody was raised using the N terminal of SPPL2 corresponding to a region with amino acids VARGNCTFYEKVRLAQGSGARGLLIVSRERLVPPGGNKTQYDEIGIPVAL
  • 应用备注

    WB: 1 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    SPPL2B Blocking Peptide, (ABIN5616378), is also available for use as a blocking control in assays to test for specificity of this SPPL2B antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SPPL0 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))

    别名

    SPPL2B

    背景

    SPPL2B is a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways.

    分子量

    56 kDa (MW of target protein)
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