AIF 抗体 (C-Term)
Quick Overview for AIF 抗体 (C-Term) (ABIN634586)
抗原
See all AIF (AIFM1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
特异性
- PDCD8 antibody was raised against the C terminal Of Pdcd8
-
纯化方法
- Affinity purified
-
免疫原
- PDCD8 antibody was raised using the C terminal Of Pdcd8 corresponding to a region with amino acids VDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEASEITIPPST
-
-
-
-
应用备注
-
WB: 0.25 µg/mL
Optimal conditions should be determined by the investigator. -
说明
-
PDCD8 Blocking Peptide, (ABIN5615270), is also available for use as a blocking control in assays to test for specificity of this PDCD8 antibody
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PDCD8 antibody in PBS
-
浓度
- Lot specific
-
缓冲液
- PBS
-
注意事项
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
-
-
- AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
-
别名
- PDCD8
-
背景
- AIFM1 (PDCD8) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, AIFM1 induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.
-
分子量
- 36 kDa (MW of target protein)
-
途径
- Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effect
抗原
-