RHOC 抗体 (N-Term)
Quick Overview for RHOC 抗体 (N-Term) (ABIN634331)
抗原
See all RHOC 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- RHOC antibody was raised against the N terminal of RHOC
-
纯化方法
- Affinity purified
-
免疫原
- RHOC antibody was raised using the N terminal of RHOC corresponding to a region with amino acids VPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCF
-
-
-
-
应用备注
-
WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
-
RHOC Blocking Peptide, (ABIN5615860), is also available for use as a blocking control in assays to test for specificity of this RHOC antibody
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of RHOC antibody in PBS
-
浓度
- Lot specific
-
缓冲液
- PBS
-
注意事项
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
-
-
- RHOC (Ras Homolog Gene Family, Member C (RHOC))
-
别名
- RHOC
-
背景
- RHOC Is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. RHOC is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of RHOC is associated with tumor cell proliferation and metastasis.
-
分子量
- 22 kDa (MW of target protein)
-
途径
- WNT signaling, Cell-Cell Junction Organization
抗原
-