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RHOC 抗体 (N-Term)

This anti-RHOC antibody is a 兔 多克隆 antibody detecting RHOC in WB. Suitable for 人, 小鼠, 大鼠, 犬, Drosophila melanogaster 和 C. elegans.
产品编号 ABIN634331
发货至: 中国

Quick Overview for RHOC 抗体 (N-Term) (ABIN634331)

抗原

See all RHOC 抗体
RHOC (Ras Homolog Gene Family, Member C (RHOC))

适用

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人, 小鼠, 大鼠, 犬, Drosophila melanogaster, C. elegans

宿主

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克隆类型

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多克隆

标记

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This RHOC antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    特异性

    RHOC antibody was raised against the N terminal of RHOC

    纯化方法

    Affinity purified

    免疫原

    RHOC antibody was raised using the N terminal of RHOC corresponding to a region with amino acids VPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCF
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    RHOC Blocking Peptide, (ABIN5615860), is also available for use as a blocking control in assays to test for specificity of this RHOC antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of RHOC antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    RHOC (Ras Homolog Gene Family, Member C (RHOC))

    别名

    RHOC

    背景

    RHOC Is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. RHOC is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of RHOC is associated with tumor cell proliferation and metastasis.

    分子量

    22 kDa (MW of target protein)

    途径

    WNT signaling, Cell-Cell Junction Organization
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