NCF4 抗体 (Middle Region)
Quick Overview for NCF4 抗体 (Middle Region) (ABIN634326)
抗原
See all NCF4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- NCF4 antibody was raised against the middle region of NCF4
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纯化方法
- Affinity purified
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免疫原
- NCF4 antibody was raised using the middle region of NCF4 corresponding to a region with amino acids TGIFPLSFVKILKDFPEEDDPTNWLRCYYYEDTISTIKSVAWEGGACPAF
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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NCF4 Blocking Peptide, (ABIN5614930), is also available for use as a blocking control in assays to test for specificity of this NCF4 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of NCF4 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- NCF4 (Neutrophil Cytosolic Factor 4, 40kDa (NCF4))
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别名
- NCF4
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背景
- NCF4 is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling event.
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分子量
- 39 kDa (MW of target protein)
抗原
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