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NCF4 抗体 (Middle Region)

This anti-NCF4 antibody is a 兔 多克隆 antibody detecting NCF4 in WB. Suitable for 人.
产品编号 ABIN634326
发货至: 中国

Quick Overview for NCF4 抗体 (Middle Region) (ABIN634326)

抗原

See all NCF4 抗体
NCF4 (Neutrophil Cytosolic Factor 4, 40kDa (NCF4))

适用

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宿主

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克隆类型

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多克隆

标记

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This NCF4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    特异性

    NCF4 antibody was raised against the middle region of NCF4

    纯化方法

    Affinity purified

    免疫原

    NCF4 antibody was raised using the middle region of NCF4 corresponding to a region with amino acids TGIFPLSFVKILKDFPEEDDPTNWLRCYYYEDTISTIKSVAWEGGACPAF
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    NCF4 Blocking Peptide, (ABIN5614930), is also available for use as a blocking control in assays to test for specificity of this NCF4 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of NCF4 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    NCF4 (Neutrophil Cytosolic Factor 4, 40kDa (NCF4))

    别名

    NCF4

    背景

    NCF4 is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling event.

    分子量

    39 kDa (MW of target protein)
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