NCF4 抗体 (N-Term)
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- 抗原 See all NCF4 抗体
- NCF4 (Neutrophil Cytosolic Factor 4, 40kDa (NCF4))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NCF4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- NCF4 antibody was raised against the N terminal of NCF4
- 纯化方法
- Affinity purified
- 免疫原
- NCF4 antibody was raised using the N terminal of NCF4 corresponding to a region with amino acids SKYLIYRRYRQFHALQSKLEERFGPDSKSSALACTLPTLPAKVYVGVKQE
- Top Product
- Discover our top product NCF4 Primary Antibody
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- 应用备注
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WB: 0.25 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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NCF4 Blocking Peptide, catalog no. 33R-8572, is also available for use as a blocking control in assays to test for specificity of this NCF4 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of NCF4 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- NCF4 (Neutrophil Cytosolic Factor 4, 40kDa (NCF4))
- 别名
- NCF4 (NCF4 产品)
- 别名
- p40phox antibody, AI451400 antibody, NCF antibody, P40PHOX antibody, SH3PXD4 antibody, neutrophil cytosolic factor 4 antibody, ncf4 antibody, Ncf4 antibody, NCF4 antibody
- 背景
- NCF4 is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling event.
- 分子量
- 39 kDa (MW of target protein)
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