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TBK1 抗体 (N-Term)

This anti-TBK1 antibody is a 兔 多克隆 antibody detecting TBK1 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN634305
发货至: 中国

Quick Overview for TBK1 抗体 (N-Term) (ABIN634305)

抗原

See all TBK1 抗体
TBK1 (TANK-Binding Kinase 1 (TBK1))

适用

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  • 43
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人, 小鼠, 大鼠

宿主

  • 81
  • 4
  • 1

克隆类型

  • 74
  • 12
多克隆

标记

  • 57
  • 7
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  • 2
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  • 1
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  • 1
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This TBK1 antibody is un-conjugated

应用范围

  • 63
  • 48
  • 38
  • 13
  • 12
  • 9
  • 6
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 10
    • 9
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    N-Term

    特异性

    TBK1 antibody was raised against the N terminal of TBK1

    纯化方法

    Affinity purified

    免疫原

    TBK1 antibody was raised using the N terminal of TBK1 corresponding to a region with amino acids EEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGM
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    TBK1 Blocking Peptide, (ABIN937738), is also available for use as a blocking control in assays to test for specificity of this TBK1 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TBK1 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    TBK1 (TANK-Binding Kinase 1 (TBK1))

    别名

    TBK1

    背景

    The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. TBK1 is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. For example, the protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK.

    分子量

    84 kDa (MW of target protein)

    途径

    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
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