TdT 抗体 (N-Term)
Quick Overview for TdT 抗体 (N-Term) (ABIN634239)
抗原
See all TdT (DNTT) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- DNTT antibody was raised against the N terminal of DNTT
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纯化方法
- Affinity purified
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免疫原
- DNTT antibody was raised using the N terminal of DNTT corresponding to a region with amino acids FQDLVVFILEKKMGTTRRAFLMELARRKGFRVENELSDSVTHIVAENNSG
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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DNTT Blocking Peptide, (ABIN938414), is also available for use as a blocking control in assays to test for specificity of this DNTT antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of DNTT antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
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别名
- DNTT
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背景
- DNTT is a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, DNTT is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor geneegments.
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分子量
- 58 kDa (MW of target protein)
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途径
- DNA Damage Repair
抗原
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