MCTS1 抗体 (N-Term)
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Quick Overview for MCTS1 抗体 (N-Term) (ABIN634224)
抗原
See all MCTS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- MCTS1 antibody was raised against the N terminal of MCTS1
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纯化方法
- Affinity purified
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免疫原
- MCTS1 antibody was raised using the N terminal of MCTS1 corresponding to a region with amino acids MFKKFDEKENVSNCIQLKTSVIKGIKNQLIEQFPGIEPWLNQIMPKKDPV
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anti-Malignant T Cell Amplified Sequence 1 (MCTS1) (AA 1-181) antibody
MCTS1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2G2 unconjugated
anti-Malignant T Cell Amplified Sequence 1 (MCTS1) antibodyMCTS1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Malignant T Cell Amplified Sequence 1 (MCTS1) (AA 1-181) antibodyMCTS1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Malignant T Cell Amplified Sequence 1 (MCTS1) (AA 1-30), (N-Term) antibodyMCTS1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB20015 unconjugated
anti-Malignant T Cell Amplified Sequence 1 (MCTS1) (AA 1-181) antibodyMCTS1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G1-2A2 unconjugated
anti-Malignant T Cell Amplified Sequence 1 (MCTS1) (N-Term) antibodyVerified MCTS1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Malignant T Cell Amplified Sequence 1 (MCTS1) (N-Term) antibodyMCTS1 适用: 人, 大鼠, Cow, 犬, 豚鼠, 斑马鱼, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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MCTS1 Blocking Peptide, (ABIN5614708), is also available for use as a blocking control in assays to test for specificity of this MCTS1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MCTS1 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- MCTS1 (Malignant T Cell Amplified Sequence 1 (MCTS1))
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别名
- MCTS1
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背景
- MCTS1 is an anti-oncogene that play a role in cell cycle regulation, decreases cell doubling time and anchorage-dependent growth, shortens the duration of G1 transit time and G1/S transition. When constituvely expressed, MCTS1 increases CDK4 and CDK6 kinases activity and CCND1/cyclin D1 protein level, as well as G1 cyclin/CDK complex formation. MCTS1 plays a role as translation enhancer, and recruits the density-regulated protein/DENR and binds to the cap complex of the 5'-terminus of mRNAs, subsequently altering the mRNA translation profile, MCTS1 up-regulates protein levels of BCL2L2, TFDP1, MRE11A, CCND1 and E2F1, while mRNA levels remains constant. MCTS1 hyperactivates DNA damage signaling pathway, increased gamma-irradiation-induced phosphorylation of histone H2AX, and induces damage foci formation.
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分子量
- 20 kDa (MW of target protein)
抗原
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