RMI1 抗体
Quick Overview for RMI1 抗体 (ABIN634128)
抗原
See all RMI1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purified
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免疫原
- RMI1 antibody was raised using a synthetic peptide corresponding to a region with amino acids DGILEIPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKNTTNDLVTAEA
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anti-Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) (AA 1-470) antibody
RMI1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) (AA 181-443) antibodyRMI1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) (AA 1-379) antibodyRMI1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) (AA 71-120) antibodyRMI1 适用: 人, 小鼠, 犬, 马, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) (AA 1-350) antibodyRMI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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RMI1 Blocking Peptide, catalog no. 33R-1953, is also available for use as a blocking control in assays to test for specificity of this RMI1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of RMI1 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- RMI1 (Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1))
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别名
- RMI1
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背景
- RMI1 is an essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. RMI1 promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. RMI1 is required for BLM phosphorylation during mitosis. Within the BLM complex, RMI1 is required for BLM and TOP3A stability.
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分子量
- 70 kDa (MW of target protein)
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途径
- DNA Damage Repair
抗原
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