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Prohibitin 抗体 (C-Term)

The 兔 多克隆 anti-Prohibitin antibody (ABIN634116) specifically detects Prohibitin in WB 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN634116
发货至: 中国
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Quick Overview for Prohibitin 抗体 (C-Term) (ABIN634116)

抗原

See all Prohibitin (PHB) 抗体
Prohibitin (PHB)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Prohibitin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    特异性

    Prohibitin antibody was raised against the C terminal of PHB

    纯化方法

    Affinity purified

    免疫原

    Prohibitin antibody was raised using the C terminal of PHB corresponding to a region with amino acids AEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLS
  • 应用备注

    WB: 1-2 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    Prohibitin Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this Prohibitin antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PHB antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    Prohibitin (PHB)

    别名

    Prohibitin

    背景

    Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.

    分子量

    30 kDa (MW of target protein)

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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