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NXF1 抗体 (N-Term)

This 兔 多克隆 anti-NXF1 antibody specifically detects NXF1 in WB. The antibody is reactive with 人 和 犬 samples.
产品编号 ABIN633230
发货至: 中国
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Quick Overview for NXF1 抗体 (N-Term) (ABIN633230)

抗原

See all NXF1 抗体
NXF1 (Nuclear RNA Export Factor 1 (NXF1))

适用

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人, 犬

宿主

  • 67
  • 1

克隆类型

  • 47
  • 21
多克隆

标记

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This NXF1 antibody is un-conjugated

应用范围

  • 49
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  • 1
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Western Blotting (WB)
  • 抗原表位

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    N-Term

    特异性

    NXF1 antibody was raised against the N terminal of NXF1

    纯化方法

    Affinity purified

    免疫原

    NXF1 antibody was raised using the N terminal of NXF1 corresponding to a region with amino acids RPNRRGDTWHDRDRIHVTVRRDRAPPERGGAGTSQDGTSKNWFKITIPYG
  • 应用备注

    WB: 0.5 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    NXF1 Blocking Peptide, (ABIN5615091), is also available for use as a blocking control in assays to test for specificity of this NXF1 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of NXF1 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    NXF1 (Nuclear RNA Export Factor 1 (NXF1))

    别名

    NXF1

    背景

    NXF1 is one member of a family of nuclear RNA export factor. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. NXF1 shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. NXF1 overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.

    分子量

    68 kDa (MW of target protein)
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