TWEAK 抗体
Our Local Distributor
北京 101111
Quick Overview for TWEAK 抗体 (ABIN633179)
抗原
See all TWEAK (TNFSF12) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Affinity purified
-
免疫原
- TNFSF12 antibody was raised using a synthetic peptide corresponding to a region with amino acids LGLLLAVVSLGSRASLSAQEPAQEELVAEEDQDPSELNPQTEESQDPAPF
-
-
-
-
应用备注
-
WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
-
TNFSF12 Blocking Peptide, (ABIN940372), is also available for use as a blocking control in assays to test for specificity of this TNFSF12 antibody
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TNFSF12 antibody in PBS
-
浓度
- Lot specific
-
缓冲液
- PBS
-
注意事项
- Avoid repeated freeze/thaw cycles.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
-
-
- TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
-
别名
- TNFSF12
-
背景
- TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family.
-
分子量
- 17 kDa (MW of target protein)
-
途径
- Apoptosis
抗原
-