Ensa 抗体 (N-Term)
Quick Overview for Ensa 抗体 (N-Term) (ABIN633083)
抗原
See all Ensa (ENSA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- ENSA antibody was raised against the N terminal of ENSA
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纯化方法
- Affinity purified
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免疫原
- ENSA antibody was raised using the N terminal of ENSA corresponding to a region with amino acids MAGGLGCDVCYWFVEDTQEKEGILPERAEEAKLKAKYPSLGQKPGGSDFL
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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ENSA Blocking Peptide, (ABIN5613379), is also available for use as a blocking control in assays to test for specificity of this ENSA antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ENSA antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Ensa (ENSA) (Endosulfine alpha (ENSA))
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别名
- ENSA
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背景
- The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.
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分子量
- 12 kDa (MW of target protein)
抗原
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