PLAT 抗体 (Middle Region)
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北京 101111
Quick Overview for PLAT 抗体 (Middle Region) (ABIN632631)
抗原
See all PLAT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- PLAT antibody was raised against the middle region of PLAT
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纯化方法
- Affinity purified
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免疫原
- PLAT antibody was raised using the middle region of PLAT corresponding to a region with amino acids TVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSR
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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PLAT Blocking Peptide, (ABIN5615407), is also available for use as a blocking control in assays to test for specificity of this PLAT antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PLAT antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- PLAT (Plasminogen Activator, Tissue (PLAT))
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别名
- PLAT
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背景
- This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
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分子量
- 53 kDa (MW of target protein)
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途径
- Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome
抗原
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