BPNT1 抗体
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- 抗原 See all BPNT1 抗体
- BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BPNT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purified
- 免疫原
- BPNT1 antibody was raised using a synthetic peptide corresponding to a region with amino acids DRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIP
- Top Product
- Discover our top product BPNT1 Primary Antibody
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- 应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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BPNT1 Blocking Peptide, catalog no. 33R-2153, is also available for use as a blocking control in assays to test for specificity of this BPNT1 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of BPNT1 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
- 别名
- BPNT1 (BPNT1 产品)
- 别名
- BPNT1 antibody, PIP antibody, Sal3 antibody, BPntase antibody, 3'(2'), 5'-bisphosphate nucleotidase 1 antibody, bisphosphate 3'-nucleotidase 1 antibody, BPNT1 antibody, bpnt1.L antibody, Bpnt1 antibody
- 背景
- BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
- 分子量
- 29 kDa (MW of target protein)
- 途径
- Inositol Metabolic Process
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