BPNT1 抗体
Quick Overview for BPNT1 抗体 (ABIN631707)
抗原
See all BPNT1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purified
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免疫原
- BPNT1 antibody was raised using a synthetic peptide corresponding to a region with amino acids DRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIP
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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BPNT1 Blocking Peptide, (ABIN937539), is also available for use as a blocking control in assays to test for specificity of this BPNT1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of BPNT1 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
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别名
- BPNT1
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背景
- BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
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分子量
- 29 kDa (MW of target protein)
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途径
- Inositol Metabolic Process
抗原
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