GCLC 抗体 (N-Term)
Quick Overview for GCLC 抗体 (N-Term) (ABIN631566)
抗原
See all GCLC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- GCLC antibody was raised against the N terminal of GCLC
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纯化方法
- Affinity purified
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免疫原
- GCLC antibody was raised using the N terminal of GCLC corresponding to a region with amino acids VLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTVEAN
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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GCLC Blocking Peptide, (ABIN5613739), is also available for use as a blocking control in assays to test for specificity of this GCLC antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of GCLC antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
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别名
- GCLC
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背景
- Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. GCLC is the catalytic subunit of 637 amino acids with a calculated molecular weight of 72.773 kDa. Deficiency of gamma-glutamylcysteine synthetase in human is associated with enzymopathic hemolytic anemia.
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分子量
- 73 kDa (MW of target protein)
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途径
- Cell RedoxHomeostasis
抗原
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