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GCLC 抗体 (N-Term)

This anti-GCLC antibody is a 兔 多克隆 antibody detecting GCLC in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN631566
发货至: 中国

Quick Overview for GCLC 抗体 (N-Term) (ABIN631566)

抗原

See all GCLC 抗体
GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This GCLC antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    特异性

    GCLC antibody was raised against the N terminal of GCLC

    纯化方法

    Affinity purified

    免疫原

    GCLC antibody was raised using the N terminal of GCLC corresponding to a region with amino acids VLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTVEAN
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    GCLC Blocking Peptide, (ABIN5613739), is also available for use as a blocking control in assays to test for specificity of this GCLC antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of GCLC antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))

    别名

    GCLC

    背景

    Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. GCLC is the catalytic subunit of 637 amino acids with a calculated molecular weight of 72.773 kDa. Deficiency of gamma-glutamylcysteine synthetase in human is associated with enzymopathic hemolytic anemia.

    分子量

    73 kDa (MW of target protein)

    途径

    Cell RedoxHomeostasis
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