METAP2 抗体 (N-Term)
Quick Overview for METAP2 抗体 (N-Term) (ABIN631470)
抗原
See all METAP2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- METAP2 antibody was raised against the N terminal of METAP2
-
纯化方法
- Affinity purified
-
免疫原
- METAP2 antibody was raised using the N terminal of METAP2 corresponding to a region with amino acids ATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGR
-
-
-
-
应用备注
-
WB: 0.5 µg/mL
Optimal conditions should be determined by the investigator. -
说明
-
METAP2 Blocking Peptide, (ABIN936942), is also available for use as a blocking control in assays to test for specificity of this METAP2 antibody
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of METAP2 antibody in PBS
-
浓度
- Lot specific
-
缓冲液
- PBS
-
注意事项
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
-
-
- METAP2 (Methionyl Aminopeptidase 2 (METAP2))
-
别名
- METAP2
-
背景
- METAP2 is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site.
-
分子量
- 53 kDa (MW of target protein)
-
途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
-