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CHN2 抗体

The 兔 多克隆 anti-CHN2 antibody is suitable to detect CHN2 in samples from 人, 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN631409
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CHN2 抗体 (ABIN631409)

抗原

See all CHN2 抗体
CHN2 (Chimerin (Chimaerin) 2 (CHN2))

适用

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人, 小鼠, 大鼠

宿主

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  • 1

克隆类型

  • 26
多克隆

标记

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This CHN2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 纯化方法

    Affinity purified

    免疫原

    CHN2 antibody was raised using a synthetic peptide corresponding to a region with amino acids AFGVKVGVKGGFLWPPLKLFACSQISSLVRRAALTHNDNHFNYEKTHNFK
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    CHN2 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CHN2 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CHN2 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    CHN2 (Chimerin (Chimaerin) 2 (CHN2))

    别名

    CHN2

    背景

    CHN2 is a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. CHN2 plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men.

    分子量

    38 kDa (MW of target protein)
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