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PPL 抗体 (Middle Region)

This 兔 多克隆 antibody specifically detects PPL in WB. It exhibits reactivity toward 人.
产品编号 ABIN631225
发货至: 中国
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Quick Overview for PPL 抗体 (Middle Region) (ABIN631225)

抗原

See all PPL 抗体
PPL (Periplakin (PPL))

适用

  • 32
  • 9
  • 7
  • 1

宿主

  • 32
  • 2

克隆类型

  • 34
多克隆

标记

  • 25
  • 3
  • 2
  • 2
  • 1
  • 1
This PPL antibody is un-conjugated

应用范围

  • 31
  • 19
  • 10
  • 7
  • 6
  • 5
  • 4
  • 2
Western Blotting (WB)
  • 抗原表位

    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    特异性

    Periplakin antibody was raised against the middle region of PPL

    纯化方法

    Affinity purified

    免疫原

    Periplakin antibody was raised using the middle region of PPL corresponding to a region with amino acids EKSRAQEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQEEELSF
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    Periplakin Blocking Peptide, (ABIN937909), is also available for use as a blocking control in assays to test for specificity of this Periplakin antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PPL antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    PPL (Periplakin (PPL))

    别名

    Periplakin

    背景

    PPL is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.

    分子量

    205 kDa (MW of target protein)
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