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OPTN 抗体 (C-Term)

This anti-OPTN antibody is a 兔 多克隆 antibody detecting OPTN in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN631194
发货至: 中国

Quick Overview for OPTN 抗体 (C-Term) (ABIN631194)

抗原

See all OPTN 抗体
OPTN (Optineurin (OPTN))

适用

  • 54
  • 33
  • 15
  • 7
  • 6
  • 5
  • 5
  • 5
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 54
  • 5

克隆类型

  • 53
  • 6
多克隆

标记

  • 33
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This OPTN antibody is un-conjugated

应用范围

  • 50
  • 14
  • 13
  • 13
  • 13
  • 12
  • 8
  • 7
  • 5
  • 3
  • 2
Western Blotting (WB)
  • 抗原表位

    • 15
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    Optineurin antibody was raised against the C terminal of OPTN

    纯化方法

    Affinity purified

    免疫原

    Optineurin antibody was raised using the C terminal of OPTN corresponding to a region with amino acids SDQQAYLVQRGAEDRDWRQQRNIPIHSCPKCGEVLPDIDTLQIHVMDCII
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    Optineurin Blocking Peptide, (ABIN5615129), is also available for use as a blocking control in assays to test for specificity of this Optineurin antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of OPTN antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    OPTN (Optineurin (OPTN))

    别名

    Optineurin

    背景

    OPTN is the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins.

    分子量

    66 kDa (MW of target protein)

    途径

    M Phase
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