OPTN 抗体 (C-Term)
Quick Overview for OPTN 抗体 (C-Term) (ABIN631194)
抗原
See all OPTN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - C-Term
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特异性
 - Optineurin antibody was raised against the C terminal of OPTN
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纯化方法
 - Affinity purified
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免疫原
 - Optineurin antibody was raised using the C terminal of OPTN corresponding to a region with amino acids SDQQAYLVQRGAEDRDWRQQRNIPIHSCPKCGEVLPDIDTLQIHVMDCII
 
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应用备注
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                        WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - 
                                            
说明
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Optineurin Blocking Peptide, (ABIN5615129), is also available for use as a blocking control in assays to test for specificity of this Optineurin antibody
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限制
 - 仅限研究用
 
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状态
 - Lyophilized
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溶解方式
 - Lyophilized powder. Add distilled water for a 1 mg/mL concentration of OPTN antibody in PBS
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浓度
 - Lot specific
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缓冲液
 - PBS
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注意事项
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                        Avoid repeated freeze/thaw cycles. 
Dilute only prior to immediate use. - 
                                            
储存条件
 - 4 °C/-20 °C
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储存方法
 - Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
 
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- OPTN (Optineurin (OPTN))
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别名
 - Optineurin
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背景
 - OPTN is the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins.
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分子量
 - 66 kDa (MW of target protein)
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途径
 - M Phase
 
抗原
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