Arrestin 3 抗体 (Middle Region)
Quick Overview for Arrestin 3 抗体 (Middle Region) (ABIN631132)
抗原
See all Arrestin 3 (ARRB2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- Arrestin B2 antibody was raised against the middle region of ARRB2
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纯化方法
- Affinity purified
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免疫原
- Arrestin B2 antibody was raised using the middle region of ARRB2 corresponding to a region with amino acids RLVIRKVQFAPEKPGPQPSAETTRHFLMSDRSLHLEASLDKELYYHGEPL
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anti-Arrestin, beta 2 (ARRB2) (Internal Region) antibody
Verified ARRB2 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 300-409) antibodyARRB2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4D2 unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 300-400) antibodyARRB2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 300-409) antibodyARRB2 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3G1 unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 222-369) antibodyARRB2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (C-Term) antibodyARRB2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (Middle Region) antibodyARRB2 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow, 马, 兔, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 251-418) antibodyARRB2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 262-430) antibodyARRB2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 264-298) antibodyARRB2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB53542 unconjugated
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应用备注
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WB: 1 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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Arrestin B2 Blocking Peptide, (ABIN5612170), is also available for use as a blocking control in assays to test for specificity of this Arrestin B2 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ARRB2 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
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背景
- Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. ARRB2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors.
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分子量
- 44 kDa (MW of target protein)
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling
抗原
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