Arrestin 3 抗体 (Middle Region)
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北京 101111
Quick Overview for Arrestin 3 抗体 (Middle Region) (ABIN2783190)
抗原
See all Arrestin 3 (ARRB2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- ARRB2 Antibody - middle region
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序列
- RLVIRKVQFA PEKPGPQPSA ETTRHFLMSD RSLHLEASLD KELYYHGEPL
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against ARRB2. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ARRB2
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anti-Arrestin, beta 2 (ARRB2) (Internal Region) antibody
Verified ARRB2 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 300-409) antibodyARRB2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4D2 unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 300-409) antibodyARRB2 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3G1 unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 300-410) antibodyARRB2 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3G1 unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 222-369) antibodyARRB2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (Middle Region) antibodyARRB2 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 251-418) antibodyARRB2 适用: 人 WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 264-298) antibodyARRB2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB53542 unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 151-200) antibodyARRB2 适用: 人, 犬, Pig, Cow, 马, 兔, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (C-Term) antibodyARRB2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8094994
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
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别名
- ARRB2
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背景
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Background Information: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. ARRB2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors.Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Gene Name: Arrestin, beta 2
Alternative Symbols: ARB2, ARR2, BARR2
Protein Name: Beta-arrestin-2
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分子量
- 46kDa
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基因ID
- 409
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NCBI登录号
- NP_945355
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UniProt
- P32121
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling
抗原
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