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STING/TMEM173 抗体 (Middle Region)

The 兔 多克隆 anti-STING/TMEM173 antibody is suitable to detect STING/TMEM173 in samples from 人. It has been validated for WB.
产品编号 ABIN630932
发货至: 中国
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Quick Overview for STING/TMEM173 抗体 (Middle Region) (ABIN630932)

抗原

See all STING/TMEM173 (TMEM173) 抗体
STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

适用

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宿主

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克隆类型

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多克隆

标记

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This STING/TMEM173 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    特异性

    TMEM173 antibody was raised against the middle region of TMEM173

    纯化方法

    Affinity purified

    免疫原

    TMEM173 antibody was raised using the middle region of TMEM173 corresponding to a region with amino acids DPNIRFLDKLPQQTGDHAGIKDRVYSNSIYELLENGQRAGTCVLEYATPL
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    TMEM173 Blocking Peptide, (ABIN937495), is also available for use as a blocking control in assays to test for specificity of this TMEM173 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TMEM173 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

    别名

    TMEM173

    背景

    TMEM173 acts as a facilitator of innate immune signaling. It is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. TMEM173 may be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons.It also may be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). TMEM173 mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.

    分子量

    42 kDa (MW of target protein)

    途径

    Activation of Innate immune Response
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