STING/TMEM173 抗体 (Middle Region)
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- 抗原 See all STING/TMEM173 (TMEM173) 抗体
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This STING/TMEM173 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- TMEM173 antibody was raised against the middle region of TMEM173
- 纯化方法
- Affinity purified
- 免疫原
- TMEM173 antibody was raised using the middle region of TMEM173 corresponding to a region with amino acids DPNIRFLDKLPQQTGDHAGIKDRVYSNSIYELLENGQRAGTCVLEYATPL
- Top Product
- Discover our top product TMEM173 Primary Antibody
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- 应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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TMEM173 Blocking Peptide, catalog no. 33R-2109, is also available for use as a blocking control in assays to test for specificity of this TMEM173 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TMEM173 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- 别名
- TMEM173 (TMEM173 产品)
- 别名
- ERIS antibody, MITA antibody, MPYS antibody, NET23 antibody, STING antibody, 2610307O08Rik antibody, Mita antibody, RGD1562552 antibody, transmembrane protein 173 antibody, TMEM173 antibody, Tmem173 antibody
- 背景
- TMEM173 acts as a facilitator of innate immune signaling. It is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. TMEM173 may be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons.It also may be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). TMEM173 mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
- 分子量
- 42 kDa (MW of target protein)
- 途径
- Activation of Innate immune Response
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