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DTX2 抗体

This anti-DTX2 antibody is a 兔 多克隆 antibody detecting DTX2 in WB. Suitable for 人, 犬 和 斑马鱼.
产品编号 ABIN630801
发货至: 中国

Quick Overview for DTX2 抗体 (ABIN630801)

抗原

See all DTX2 抗体
DTX2 (Deltex Homolog 2 (DTX2))

适用

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人, 犬, 斑马鱼

宿主

  • 31
  • 2
  • 1

克隆类型

  • 34
多克隆

标记

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This DTX2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 纯化方法

    Affinity purified

    免疫原

    DTX2 antibody was raised using a synthetic peptide corresponding to a region with amino acids EDCGTILIVYSIPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLE
  • 应用备注

    WB: 0.25 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    DTX2 Blocking Peptide, (ABIN937691), is also available for use as a blocking control in assays to test for specificity of this DTX2 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of DTX2 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    DTX2 (Deltex Homolog 2 (DTX2))

    别名

    DTX2

    背景

    DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX2 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context and mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. It also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

    分子量

    62 kDa (MW of target protein)

    途径

    Notch Signaling
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