ABAT 抗体 (Middle Region)
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北京 101111
Quick Overview for ABAT 抗体 (Middle Region) (ABIN630787)
抗原
See all ABAT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- ABAT antibody was raised against the middle region of ABAT
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纯化方法
- Affinity purified
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免疫原
- ABAT antibody was raised using the middle region of ABAT corresponding to a region with amino acids IIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFW
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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ABAT Blocking Peptide, (ABIN939395), is also available for use as a blocking control in assays to test for specificity of this ABAT antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ABAT antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- ABAT (4-Aminobutyrate Aminotransferase (ABAT))
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别名
- ABAT
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背景
- 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50 kDa subunits complexed to pyridoxal-5-phosphate. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities.4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde
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分子量
- 55 kDa (MW of target protein)
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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