MLF1 抗体 (N-Term)
Quick Overview for MLF1 抗体 (N-Term) (ABIN630719)
抗原
See all MLF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- MLF1 antibody was raised against the N terminal of MLF1
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纯化方法
- Affinity purified
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免疫原
- MLF1 antibody was raised using the N terminal of MLF1 corresponding to a region with amino acids GRDLLSISDGRGRAHNRRGHNDGEDSLTHTDVSSFQTMDQMVSNMRNYMQ
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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MLF1 Blocking Peptide, (ABIN938907), is also available for use as a blocking control in assays to test for specificity of this MLF1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MLF1 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- MLF1 (Myeloid Leukemia Factor 1 (MLF1))
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别名
- MLF1
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背景
- MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. It interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. MLF1 suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest.It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
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分子量
- 29 kDa (MW of target protein)
抗原
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