Lamin B1 抗体 (Middle Region)
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Quick Overview for Lamin B1 抗体 (Middle Region) (ABIN630637)
抗原
See all Lamin B1 (LMNB1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- Lamin B1 antibody was raised against the middle region of LMNB1
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纯化方法
- Affinity purified
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免疫原
- Lamin B1 antibody was raised using the middle region of LMNB1 corresponding to a region with amino acids EEVAQRSTVFKTTIPEEEEEEEEAAGVVVEEELFHQQGTPRASNRSCAIM
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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Lamin B1 Blocking Peptide, (ABIN937779), is also available for use as a blocking control in assays to test for specificity of this Lamin B1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of LMNB1 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Lamin B1 (LMNB1)
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别名
- Lamin B1
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背景
- LAMNB1 encodes for one of the two B type proteins of the nuclear lamina, B1. The Vertebrate lamins consist of two types, A and B. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression.
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分子量
- 66 kDa (MW of target protein)
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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