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UBE2D2 抗体

This anti-UBE2D2 antibody is a 兔 多克隆 antibody detecting UBE2D2 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠 和 犬.
产品编号 ABIN630401
发货至: 中国

Quick Overview for UBE2D2 抗体 (ABIN630401)

抗原

See all UBE2D2 抗体
UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

适用

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人, 小鼠, 大鼠, 犬

宿主

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克隆类型

  • 56
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多克隆

标记

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This UBE2D2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 纯化方法

    Purified

    免疫原

    UBE2 D2 antibody was raised using a synthetic peptide corresponding to a region with amino acids SQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIARE
  • 应用备注

    WB: 1.25 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    UBE2D2 Blocking Peptide, (ABIN5616861), is also available for use as a blocking control in assays to test for specificity of this UBE2D2 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of UBE0 2 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

    别名

    UBE2D2

    背景

    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D2 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.SLC38A4 is found predominantly in liver and transports both cationic and neutral amino acids. The transport of cationic amino acids by SLC38A4 is Na(+) and pH independent, while the transport of neutral amino acids is Na(+) and pH dependent.

    分子量

    60 kDa (MW of target protein)

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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