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BAG2 抗体 (C-Term)

This anti-BAG2 antibody is a 兔 多克隆 antibody detecting BAG2 in WB 和 IHC. Suitable for 人, 大鼠, 小鼠, 犬 和 斑马鱼.
产品编号 ABIN630239
发货至: 中国

Quick Overview for BAG2 抗体 (C-Term) (ABIN630239)

抗原

See all BAG2 抗体
BAG2 (BCL2-Associated Athanogene 2 (BAG2))

适用

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人, 大鼠, 小鼠, 犬, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This BAG2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    特异性

    BAG2 antibody was raised against the C terminal of BAG2

    纯化方法

    Purified

    免疫原

    BAG2 antibody was raised using the C terminal of BAG2 corresponding to a region with amino acids VDQKFQSIVIGCALEDQKKIKRRLETLLRNIENSDKAIKLLEHSKGAGSK
  • 应用备注

    WB: 1.25 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    BAG2 Blocking Peptide, (ABIN5612271), is also available for use as a blocking control in assays to test for specificity of this BAG2 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of BAG2 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    BAG2 (BCL2-Associated Athanogene 2 (BAG2))

    别名

    BAG2

    背景

    BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

    分子量

    23 kDa (MW of target protein)
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