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RRM1 抗体 (N-Term)

This anti-RRM1 antibody is a 兔 多克隆 antibody detecting RRM1 in WB. Suitable for 人, 小鼠, 大鼠, 斑马鱼, 犬 和 C. elegans.
产品编号 ABIN630191
发货至: 中国

Quick Overview for RRM1 抗体 (N-Term) (ABIN630191)

抗原

See all RRM1 抗体
RRM1 (Ribonucleotide Reductase M1 (RRM1))

适用

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人, 小鼠, 大鼠, 斑马鱼, 犬, C. elegans

宿主

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克隆类型

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多克隆

标记

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This RRM1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    特异性

    RRM1 antibody was raised against the N terminal of RRM1

    纯化方法

    Purified

    免疫原

    RRM1 antibody was raised using the N terminal of RRM1 corresponding to a region with amino acids ATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHL
  • 应用备注

    WB: 1.25 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    RRM1 Blocking Peptide, (ABIN936944), is also available for use as a blocking control in assays to test for specificity of this RRM1 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of RRM1 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    RRM1 (Ribonucleotide Reductase M1 (RRM1))

    别名

    RRM1

    背景

    RRM1 is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. Its gene is located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. Its gene may play a role in malignancies and disease that involve this region.

    分子量

    90 kDa (MW of target protein)

    途径

    Positive Regulation of Endopeptidase Activity
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