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MCM6 抗体 (C-Term)

MCM6 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN630187
发货至: 中国
  • 抗原 See all MCM6 抗体
    MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))
    抗原表位
    • 12
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    C-Term
    适用
    • 45
    • 17
    • 11
    • 9
    • 7
    • 7
    • 7
    • 4
    • 2
    • 1
    • 1
    人, 犬
    宿主
    • 36
    • 5
    • 4
    克隆类型
    • 41
    • 4
    多克隆
    标记
    • 40
    • 1
    • 1
    • 1
    • 1
    • 1
    This MCM6 antibody is un-conjugated
    应用范围
    • 39
    • 29
    • 17
    • 14
    • 11
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    MCM6 antibody was raised against the C terminal of MCM6
    纯化方法
    Purified
    免疫原
    MCM6 antibody was raised using the C terminal of MCM6 corresponding to a region with amino acids RIIEKVIHRLTHYDHVLIELTQAGLKGSTEGSESYEEDPYLVVNPNYLLE
    Top Product
    Discover our top product MCM6 Primary Antibody
  • 应用备注
    WB: 1.25 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    MCM6 Blocking Peptide, catalog no. 33R-7967, is also available for use as a blocking control in assays to test for specificity of this MCM6 antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MCM6 antibody in PBS
    浓度
    Lot specific
    缓冲液
    PBS
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原
    MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))
    别名
    MCM6 (MCM6 产品)
    背景
    The protein encoded by the MCM6 gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
    分子量
    90 kDa (MW of target protein)
    途径
    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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