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MCM6 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects MCM6 in IHC 和 WB. It exhibits reactivity toward 人 和 犬.
产品编号 ABIN630187
发货至: 中国
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Quick Overview for MCM6 抗体 (C-Term) (ABIN630187)

抗原

See all MCM6 抗体
MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

适用

  • 81
  • 39
  • 33
  • 9
  • 7
  • 7
  • 7
  • 4
  • 2
  • 1
  • 1
人, 犬

宿主

  • 58
  • 19
  • 4

克隆类型

  • 43
  • 38
多克隆

标记

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  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MCM6 antibody is un-conjugated

应用范围

  • 63
  • 63
  • 35
  • 19
  • 18
  • 16
  • 14
  • 13
  • 11
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Western Blotting (WB)
  • 抗原表位

    • 12
    • 12
    • 8
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    C-Term

    特异性

    MCM6 antibody was raised against the C terminal of MCM6

    纯化方法

    Purified

    免疫原

    MCM6 antibody was raised using the C terminal of MCM6 corresponding to a region with amino acids RIIEKVIHRLTHYDHVLIELTQAGLKGSTEGSESYEEDPYLVVNPNYLLE
  • 应用备注

    WB: 1.25 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    MCM6 Blocking Peptide, (ABIN5614702), is also available for use as a blocking control in assays to test for specificity of this MCM6 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MCM6 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

    别名

    MCM6

    背景

    The protein encoded by the MCM6 gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.

    分子量

    90 kDa (MW of target protein)

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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