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MCM7 抗体 (N-Term)

This anti-MCM7 antibody is a 兔 多克隆 antibody detecting MCM7 in WB. Suitable for 人.
产品编号 ABIN630182
发货至: 中国

Quick Overview for MCM7 抗体 (N-Term) (ABIN630182)

抗原

See all MCM7 抗体
MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

适用

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宿主

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克隆类型

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多克隆

标记

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This MCM7 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    特异性

    MCM7 antibody was raised against the N terminal of MCM7

    纯化方法

    Purified

    免疫原

    MCM7 antibody was raised using the N terminal of MCM7 corresponding to a region with amino acids MALKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVALYV
  • 应用备注

    WB: 2.5 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    MCM7 Blocking Peptide, (ABIN5614704), is also available for use as a blocking control in assays to test for specificity of this MCM7 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MCM7 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

    别名

    MCM7

    背景

    MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB.

    分子量

    42 kDa (MW of target protein)

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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