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PAWR 抗体

The 兔 多克隆 anti-PAWR antibody is suitable to detect PAWR in samples from 人, 小鼠 和 大鼠.
产品编号 ABIN6298166
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PAWR 抗体 (ABIN6298166)

抗原

See all PAWR 抗体
PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))

适用

  • 35
  • 21
  • 21
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 35
  • 1

克隆类型

  • 33
  • 3
多克隆

标记

  • 22
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This PAWR antibody is un-conjugated

应用范围

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  • 原理

    Rabbit Anti-Prostate Apoptosis Response protein-4 Antibody,
  • 限制

    仅限研究用
  • 储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))

    别名

    Prostate Apoptosis Response protein-4

    背景

    Target Description: Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down- regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1.

    Gene Symbol: PAWR

    基因ID

    5074

    UniProt

    Q96IZ0
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