KNG1 抗体 (Biotin)
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- 抗原 See all KNG1 抗体
- KNG1 (Kininogen 1 (KNG1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KNG1 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA
- 原理
- Rabbit anti-Human Bradykinin [+Biotin] Antibody,
- 免疫原
- This antibody was produced from antiserum of rabbits immunized with a polypeptide immunogen. The IgG fraction was purified by Protein G/A affinity chromatography.
- 亚型
- IgG
- Top Product
- Discover our top product KNG1 Primary Antibody
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anti-Kininogen 1 (KNG1) (AA 390-644) antibody
KNG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (N-Term) antibodyKNG1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 19-380) antibodyKNG1 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 378-430) antibodyKNG1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C9 unconjugated
anti-Kininogen 1 (KNG1) (AA 148-427) antibodyKNG1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 22-379) antibodyKNG1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 390-644) antibodyKNG1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 1-427) antibodyKNG1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 1-427) antibodyKNG1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 322-427) antibodyKNG1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4A1 unconjugated
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- 应用备注
- ELISA (recommended work dilution= 1:16,000), Western Blotting (recommended work dilution= 1:1,000-5,002),
- 限制
- 仅限研究用
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- 溶解方式
- Product is supplied as a powder obtained from lyophilization of purified antibody in PBS without preservatives. Reconstitute the antibody with sterile 1 x PBS to a final concentration of 1 mg/mL.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- -20°C
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- 抗原
- KNG1 (Kininogen 1 (KNG1))
- 别名
- Kininogen-1 , Kininogen-1 light chain, Low molecular weight growth-promoting factor] (KNG1 产品)
- 背景
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Target Description: Bradykinin is a potent endothelium-dependent vasodilator, leading to a drop in blood pressure. It also causes contraction of non-vascular smooth muscle in the bronchus and gut, increases vascular permeability and is also involved in the mechanism of pain.Bradykinin also causes natriuresis, contributing to the drop in blood pressure.Bradykinin raises internal calcium levels in neocortical astrocytes causing them to release glutamate.Bradykinin is also thought to be the cause of the dry cough in some patients on angiotensin-converting enzyme (ACE) inhibitor drugs. It is thought that bradykinin is converted to inactive metabolites by ACE, therefore inhibition of this enzyme leads to increased levels of bradykinin, which causes a dry cough via bronchoconstriction. This refractory cough is a common cause for stopping ACE inhibitor therapy, in which case angiotensin II receptor antagonists (ARBs) are the next line of treatment.Overactivation of bradykinin is thought to play a role in a rare disease called hereditary angioedema, formerly known as hereditary angio-neurotic edema.
Gene Symbol: KNG1///BDK///KNG
- 基因ID
- 3827
- UniProt
- P01042
- 途径
- ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process
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