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NEFH 抗体

This anti-NEFH antibody is a 小鼠 单克隆 antibody detecting NEFH in IHC 和 FACS. Suitable for 人, 大鼠, 小鼠, 小鸡 和 Pig.
产品编号 ABIN6297788
发货至: 中国

Quick Overview for NEFH 抗体 (ABIN6297788)

抗原

See all NEFH 抗体
NEFH (Neurofilament, Heavy Polypeptide (NEFH))

适用

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人, 大鼠, 小鼠, 小鸡, Pig

宿主

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  • 9
小鼠

克隆类型

  • 99
  • 54
单克隆

标记

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This NEFH antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 原理

    Mouse anti-Human/Mouse/Rat/Chicken/Pig Neurofilament Heavy Antibody [Sodium Azide Free]

    特异性

    Cytoplasmic

    纯化方法

    The triton-X 100 insoluble protein fraction of rat brain was used as the immunogen for this Neurofilament Heavy antibody.

    免疫原

    The triton-X 100 insoluble protein fraction of rat brain was used as the immunogen for this Neurofilament Heavy antibody.
  • 应用备注

    FACS: 0.5-1 μg/million cells
    IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
    Prediluted format: incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS ( pH 7.4), BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    NEFH (Neurofilament, Heavy Polypeptide (NEFH))

    别名

    Neurofilament heavy polypeptide

    背景

    Target Description: This antibody reacts with a 200 kDa protein, identified as heavy subunit of neurofilaments, or NF-H. Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H), plus alpha internexin or peripherin. Each neurofilament subunit contains a globular head, an alpha helical rod domain, and variable tail domains that differ in length and amino acid content.Neurofilament antibody stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for neurofilament antibody. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and cell carcinomas of the lung also express neurofilament.

    Gene Symbol: NEFH///KIAA0845///NFH

    基因ID

    4744

    UniProt

    P12036
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