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CD63 抗体

This anti-CD63 antibody is a 小鼠 单克隆 antibody detecting CD63 in FACS, WB, IHC 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN6297776
发货至: 中国

Quick Overview for CD63 抗体 (ABIN6297776)

抗原

See all CD63 抗体
CD63

适用

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人, 小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD63 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    Mouse anti-Human/Mouse CD63 Antibody [Sodium Azide Free]

    特异性

    Cytoplasmic

    纯化方法

    The smooth plasma membrane fraction of MeWo cells was used as the immunogen for this CD63 antibody.

    免疫原

    The smooth plasma membrane fraction of MeWo cells was used as the immunogen for this CD63 antibody.
  • 应用备注

    FACS: 0.5-1 μg/million cells
    IF: 0.5-1 μg/mL
    WB: 1-2 μg/mL
    IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
    Prediluted format: incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS ( pH 7.4), BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    CD63

    别名

    CD63 antigen

    背景

    Target Description: The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. It is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. Deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

    Gene Symbol: CD63///MLA1///TSPAN30

    基因ID

    967

    UniProt

    P08962
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