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CD63 抗体 (PE)

This anti-CD63 antibody is a 小鼠 单克隆 antibody detecting CD63 in FACS, IF 和 T. Suitable for 人 和 小鼠.
产品编号 ABIN6297775
发货至: 中国

Quick Overview for CD63 抗体 (PE) (ABIN6297775)

抗原

See all CD63 抗体
CD63

适用

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人, 小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD63 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)
  • 原理

    Mouse anti-Human/Mouse CD63 Antibody [PE Conjugated]

    特异性

    Cytoplasmic

    纯化方法

    The smooth plasma membrane fraction of MeWo cells was used as the immunogen for this CD63 antibody.

    免疫原

    The smooth plasma membrane fraction of MeWo cells was used as the immunogen for this CD63 antibody.
  • 应用备注

    Flow Cytometry: 5 µL/test/million cells or 5 µL/test/100 µL of whole blood
    Immunofluorescence: 1:50-1:100 for 30 minutes at RT

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2-8°C. The conjugate is light-sensitive, protect from light.
  • 抗原

    CD63

    别名

    CD63 antigen

    背景

    Target Description: The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

    Gene Symbol: CD63///MLA1///TSPAN30

    基因ID

    967

    UniProt

    P08962
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