CD63 抗体 (PE)
Quick Overview for CD63 抗体 (PE) (ABIN6297775)
抗原
See all CD63 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Mouse CD63 Antibody [PE Conjugated]
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特异性
- Cytoplasmic
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纯化方法
- The smooth plasma membrane fraction of MeWo cells was used as the immunogen for this CD63 antibody.
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免疫原
- The smooth plasma membrane fraction of MeWo cells was used as the immunogen for this CD63 antibody.
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应用备注
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Flow Cytometry: 5 µL/test/million cells or 5 µL/test/100 µL of whole blood
Immunofluorescence: 1:50-1:100 for 30 minutes at RT -
限制
- 仅限研究用
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缓冲液
- In 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C. The conjugate is light-sensitive, protect from light.
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- CD63
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别名
- CD63 antigen
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背景
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Target Description: The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
Gene Symbol: CD63///MLA1///TSPAN30
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基因ID
- 967
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UniProt
- P08962
抗原
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