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CD63 抗体

This anti-CD63 antibody is a 小鼠 单克隆 antibody detecting CD63 in FACS, WB, IHC 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN6297773
发货至: 中国

Quick Overview for CD63 抗体 (ABIN6297773)

抗原

See all CD63 抗体
CD63

适用

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人, 小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD63 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    Mouse anti-Human/Mouse CD63 Antibody [Sodium Azide Free]

    特异性

    Cell Surface & Cytoplasmic

    纯化方法

    The smooth plasma membrane fraction of MeWo cells was used as the immunogen for this anti-CD63 antibody.

    免疫原

    The smooth plasma membrane fraction of MeWo cells was used as the immunogen for this anti-CD63 antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Western blot: 2-4 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
    Prediluted format: incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    CD63

    别名

    CD63 antigen

    背景

    Target Description: The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

    Gene Symbol: CD63///MLA1///TSPAN30

    基因ID

    967

    UniProt

    P08962
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