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CD63 抗体

The 小鼠 单克隆 anti-CD63 antibody (ABIN6297771) specifically detects CD63 in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN6297771
发货至: 中国
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Room 801-803
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Quick Overview for CD63 抗体 (ABIN6297771)

抗原

See all CD63 抗体
CD63

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD63 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 原理

    Mouse anti-Human CD63 Antibody Cocktail [IHC only]

    特异性

    Cytoplasmic

    纯化方法

    The smooth plasma membrane fraction of MeWo cells (NKI/C3) and recombinant human full-length protein (LAMP3/968) were used as the immunogen for the CD63 antibody cocktail.

    免疫原

    The smooth plasma membrane fraction of MeWo cells (NKI/C3) and recombinant human full-length protein (LAMP3/968) were used as the immunogen for the CD63 antibody cocktail.
  • 应用备注

    Prediluted format : incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 缓冲液

    Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    CD63

    别名

    CD63 antigen

    背景

    Target Description: This mAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

    Gene Symbol: CD63///MLA1///TSPAN30

    基因ID

    967

    UniProt

    P08962
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