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CD20 抗体

MS4A1 适用: 人 FACS, IF, Func 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6297751
发货至: 中国
  • 抗原 See all CD20 (MS4A1) 抗体
    CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
    适用
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    宿主
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    小鼠
    克隆类型
    • 209
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    单克隆
    标记
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    This CD20 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
    原理
    Mouse anti-Human CD20 Antibody [Sodium Azide Free]
    特异性
    Predominantly cell surface with some cytoplasmic
    纯化方法
    The lymphoblastoid cell line Daudi was used as the immunogen for this CD20 antibody.
    免疫原
    The lymphoblastoid cell line Daudi was used as the immunogen for this CD20 antibody.
    Top Product
    Discover our top product MS4A1 Primary Antibody
  • 应用备注
    Functional Testing: order azide-free format
    FACS: 0.5-1 μg/million cells
    IF: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    In 1X PBS ( pH 7.4), BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原
    CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
    别名
    B-lymphocyte antigen CD20 (MS4A1 产品)
    别名
    B1 antibody, Bp35 antibody, CD20 antibody, CVID5 antibody, LEU-16 antibody, MS4A2 antibody, S7 antibody, AA960661 antibody, Cd20 antibody, Ly-44 antibody, Ms4a2 antibody, MS4A1 antibody, bp35 antibody, cd20 antibody, ms4a2 antibody, leu-16 antibody, ms4a4c antibody, cd20-like antibody, membrane spanning 4-domains A1 antibody, membrane-spanning 4-domains, subfamily A, member 1 antibody, B-lymphocyte antigen CD20 antibody, MS4A1 antibody, Ms4a1 antibody, ms4a1 antibody, LOC101694281 antibody
    背景

    Target Description: This antibody recognizes a protein of 33-37 kDa, identified as CD20 (Workshop V, Code CD20.12). The antibody recognizes the extracellular domain of CD20. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This antibody can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood, Bcell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of Bcells and its expression is restricted to normal and neoplastic Bcells, being absent from all other leukocytes and tissues. It is expressed by pre Bcells and persists during all stages of Bcell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting Bcells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as a calcium channel involved in Bcell activation and cell cycle progression.

    Gene Symbol: MS4A1///CD20

    基因ID
    931
    UniProt
    P11836
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