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CD20 抗体 (PE)

MS4A1 适用: 人 FACS, IF, T 宿主: 小鼠 Monoclonal PE
产品编号 ABIN6297750
发货至: 中国
  • 抗原 See all CD20 (MS4A1) 抗体
    CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
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    宿主
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    小鼠
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    单克隆
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    This CD20 antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)
    原理
    Mouse anti-Human CD20 Antibody [PE Conjugated]
    特异性
    Predominantly cell surface with some cytoplasmic
    纯化方法
    The lymphoblastoid cell line Daudi was used as the immunogen for this CD20 antibody.
    免疫原
    The lymphoblastoid cell line Daudi was used as the immunogen for this CD20 antibody.
    Top Product
    Discover our top product MS4A1 Primary Antibody
  • 应用备注
    Flow Cytometry: 5 µL per test per one million cells in 0.1 mL (or 5 µL per 100 µL of whole blood)
    Immunofluorescence: 1:50-1:100
    限制
    仅限研究用
  • 缓冲液
    In 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    2-8°C. The conjugate is light-sensitive, protect from light.
  • 抗原
    CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
    别名
    B-lymphocyte antigen CD20 (MS4A1 产品)
    别名
    B1 antibody, Bp35 antibody, CD20 antibody, CVID5 antibody, LEU-16 antibody, MS4A2 antibody, S7 antibody, AA960661 antibody, Cd20 antibody, Ly-44 antibody, Ms4a2 antibody, MS4A1 antibody, bp35 antibody, cd20 antibody, ms4a2 antibody, leu-16 antibody, ms4a4c antibody, cd20-like antibody, membrane spanning 4-domains A1 antibody, membrane-spanning 4-domains, subfamily A, member 1 antibody, B-lymphocyte antigen CD20 antibody, MS4A1 antibody, Ms4a1 antibody, ms4a1 antibody, LOC101694281 antibody
    背景

    Target Description: This antibody recognizes a protein of 33-37 kDa, identified as CD20 (Workshop V, Code CD20.12). The antibody recognizes the extracellular domain of CD20. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This antibody can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood, B cell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as a calcium channel involved in B-cell activation and cell cycle progression.

    Gene Symbol: MS4A1///CD20

    基因ID
    931
    UniProt
    P11836
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