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CD74 抗体

CD74 适用: 人, 小鼠 FACS, IF, IHC 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6297717
发货至: 中国
  • 抗原 See all CD74 抗体
    CD74 (HLA-DR-gamma (CD74))
    适用
    • 183
    • 64
    • 13
    • 11
    人, 小鼠
    宿主
    • 121
    • 80
    • 3
    • 2
    小鼠
    克隆类型
    • 137
    • 67
    • 2
    单克隆
    标记
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    This CD74 antibody is un-conjugated
    应用范围
    • 126
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    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
    原理
    Mouse anti-Human/Mouse CD74 Antibody [Sodium Azide Free]
    特异性
    Cell surface and paranuclear globular
    纯化方法
    SU-DHL-4 lymphoma cells were used as the immunogen for this CD74 antibody.
    免疫原
    SU-DHL-4 lymphoma cells were used as the immunogen for this CD74 antibody.
    Top Product
    Discover our top product CD74 Primary Antibody
  • 应用备注
    FACS: 0.5-1 μg/million cells
    IF: 1-2 μg/mL
    IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
    Prediluted format: incubate for 30 min at RT (2)
    限制
    仅限研究用
  • 缓冲液
    In 1X PBS ( pH 7.4), BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原
    CD74 (HLA-DR-gamma (CD74))
    别名
    HLA class II histocompatibility antigen gamma chain (CD74 产品)
    别名
    DHLAG antibody, HLADG antibody, II antibody, Ia-GAMMA antibody, CLIP antibody, Ii antibody, INVG34 antibody, Iclp-1 antibody, iclp1 antibody, wu:fb11f09 antibody, wu:fb12a01 antibody, wu:fb13d06 antibody, wu:fk94e07 antibody, Iclp-2 antibody, cd74 antibody, iclp2 antibody, zgc:123161 antibody, CD74 molecule antibody, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) antibody, CD74 molecule, major histocompatibility complex, class II invariant chain a antibody, CD74 molecule, major histocompatibility complex, class II invariant chain b antibody, CD74 antibody, Cd74 antibody, cd74a antibody, cd74b antibody
    背景

    Target Description: CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. CD74 antibody stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. antibody to CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+).

    Gene Symbol: CD74///DHLAG

    基因ID
    972
    UniProt
    P04233
    途径
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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